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Servier Laboratories (French: Laboratoires Servier, often abbreviated to Servier) is a privately owned French pharmaceutical company that specialises in medication for cardiological and rheumatological conditions, as well as for diabetes and clinical depression.〔(【引用サイトリンク】title=SERVIER - Pharmaceutical company specialized in cardiology, diabetes, rheumatology, depression )〕 The consolidated turnover for the 2005/2006 financial year was €3.5 billion. Servier is the leading French independent pharmaceutical company, and the second largest French pharmaceutical company worldwide. It has branches in 140 countries, achieving 82% of its sales outside France.〔 The annual sales of its ACE inhibitor, Coversyl (perindopril), in 2006 and 2007 exceeded 1 billion US dollars, making it Servier's highest-selling product. The company reportedly invests a little under 25% of its turnover in research and development, which occupies 3,000 of its 20,000 employees worldwide. The company's production sites produced 670 million drug boxes in 2006.〔 The Servier Clinical Support Unit in Gidy (near Orléans), which produces drugs for clinical trials, is the largest unit of its kind in Europe.〔(【引用サイトリンク】title=Servier UK - Key figures )〕 Servier Laboratories is a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA). ==Product portfolio== Notable products: *Gliclazide (Diamicron, Diamicron MR) — antidiabetic drug *Indapamide (Fludex SR, Natrilex SR, Lozide) — diuretic *Ivabradine (Procoralan) — antianginal drugs *Perindopril (Coversyl) — ACE inhibitor *Strontium ranelate (Protelos) — osteoporosis agent *Tianeptine (Stablon) — antidepressant, indirect alteration of AMPA and NMDA glutamate receptor activity *Trimetazidine (Vastarel MR) — antianginal drug. Other products: *Agomelatine (Valdoxan, Melitor, Thymanax) *Almitrine (Duxil, Vectarion) *Amineptine (Survector, Maneon, Directim) *Benfluorex (Mediaxal) *Carbutamide (Glucidoral) *Daflon 500 *Fenspiride (Pneumorel) *Fotemustine (Muphoran) *Fusafungine (Locabiotal) *Gliclazide (Diamicron) *Indapamide (Natrilix, Tertensif, Lozide) *Perindopril (Coversyl, Prestarium) *Perindopril/indapamide (Preterax, Coversyl Plus) *Piribedil (Trivastal retard) *Rilmenidine (Hyperium) *Sodium alginate (Pseudophage) *Sulbutiamine (Arcalion) *Tertatolol (Artex) *Vitamins (Vitathion) Mediator, an amphetamine-based Servier drug originally developed for weight loss in people with diabetes but often prescribed off-label as a dieting aid, was withdrawn from the market after being linked to 500–2000 deaths in France.〔(Article of the Figaro about Mediator )〕〔(Un doute sur la «sécurité» du Mediator dès 1998 - Libération )〕 Further investigations found that many previous safety alerts on that drug had been either missed or hushed down, possibly through improper influence of the company.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Laboratoires Servier」の詳細全文を読む スポンサード リンク
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